Neurobrucellosis: Unexpected Answer From Metagenomic Next-Generation Sequencing.

نویسندگان

  • Kanokporn Mongkolrattanothai
  • Samia N Naccache
  • Jeffrey M Bender
  • Erik Samayoa
  • Elizabeth Pham
  • Guixia Yu
  • Jennifer Dien Bard
  • Steve Miller
  • Grace Aldrovandi
  • Charles Y Chiu
چکیده

A diagnosis of brucellosis can be difficult because routine culture and serological methods exhibit variable sensitivity and specificity. We present the use of a metagenomic next- generation sequencing assay to diagnose a case of neurobrucellosis from cerebrospinal fluid, resulting in the institution of appropriate antibiotic treatment and a favorable clinical outcome.

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عنوان ژورنال:
  • Journal of the Pediatric Infectious Diseases Society

دوره 6 4  شماره 

صفحات  -

تاریخ انتشار 2017